Skip to content

We recommend that you do not collect or post samples between Tuesday 31st and Sunday 5th June.

Vitamin B12 (Active) Folate and Ferritin Blood Test

Vitamin B12 (Active) Folate and Ferritin Blood Test


This blood test measures active vitamin B12 (holotranscobalamin), folate (folic acid) and ferritin.
Blood sample 3 biomarkers included Results estimated in 4 working days from sample receipt at lab
Vitamin B12 (Active) Folate and Ferritin Blood Test
Vitamin B12 (Active) Folate and Ferritin Blood Test
Vitamin B12 (Active) Folate and Ferritin Blood Test
Vitamin B12 (Active) Folate and Ferritin Blood Test

What's included?

Biomarker profiles

  • Iron Status
  • Vitamins

Iron Status (1 Biomarker)

Vitamins (2 Biomarkers)

Special instructions

Do not take vitamin B12 for two weeks prior to this test. If your B12 is prescribed ask your doctor whether you should stop before testing. Do not take biotin supplements for 2 days prior to this test. If you are taking prescribed biotin you should discuss this with your doctor. You should take this test before you take any vitamin or mineral supplements.

From the expert

This blood test measures levels of vitamin B12 and folate which are essential water-soluble vitamins. It also tests for levels of ferritin, an important measure of iron stores in the body. All these tests are helpful in the diagnosis of anaemia.

Vitamin B12 is a water-soluble vitamin that is found in virtually all meat products and certain algae such as seaweed that helps maintain healthy nerve cells, red blood cells and is also needed to make DNA, the genetic material in all cells. Good sources of vitamin B12 include meat, salmon, cod, milk, cheese, eggs, yeast extract and some fortified breakfast cereals. As this vitamin is found almost exclusively in animal-based products, those who cut out animal products from their diet are at risk of B12 deficiency so checking their B12 levels is very important.

Vitamin B12 deficiency symptoms usually develop gradually but can worsen if the condition goes untreated, they include headaches, fatigue, pale skin and palpitations. Pernicious anaemia (an autoimmune condition) prevents absorption by stopping the production of intrinsic factor and is the leading cause of vitamin B12 deficiency.

Folate is a water-soluble vitamin important for the normal production of red blood cells and in the prevention of neural tube defects such as spina bifida in unborn babies. Folate is found in small amounts in many foods. Good sources include broccoli, Brussels sprouts, asparagus, peas, chickpeas and brown rice. Other useful sources include fortified breakfast cereals, some bread and some fruit (such as oranges and bananas).

Most people should be able to get the required amount of folate by eating a varied and balanced diet with plenty of green leafy vegetables.

Both vitamin B12 and folic acid are necessary to help break down homocysteine in the body. High levels of homocysteine are thought to be a risk factor for cardiovascular disease.

Dr Sam Rodgers MBBS, MRCGP
Chief Medical Officer

Why take this test?

  • You don't think you get enough vitamin B12 and folate in your diet
  • You have symptoms which are consistent with deficiencies in B12, folate or ferritin
  • You have raised homocysteine and want to know whether you are getting enough of these important vitamins
  • You are pregnant or planning a pregnancy want to ensure your levels are normal

Laboratories you can trust

Trusted by the NHS and private clinics alike, you can be sure of the highest testing standards from our UKAS accredited partner laboratories.

Dr Sam Rodgers - Chief Medical Officer

Expert advice with your results

Get trusted advice and comments from one of our doctors based on your results.

Your personal health centre

Your personal health centre

Discover the easy way to track your health through our online portal, View your results with doctor's advice, monitor any changes over time and see the improvements you can make to your health with simple lifestyle changes.

Questions? Let us help
Questions? Let us help

Questions? Let us help

Our customer care team is on-hand to help you find the test that's right for you. Get in touch via phone, live chat or email.


Our tests are not a substitute for seeing your doctor, especially if you are suffering symptoms. Our doctors will interpret your results based on the information you have provided, but will not diagnose, consult or provide any treatment. You will be advised to see your doctor for any necessary follow-up action.