TSH Receptor Stimulating Antibodies Blood Test

Testing for thyroid antibodies, helps to distinguish an autoimmune thyroid disease from other forms of thyroid dysfunction. Thyroid autoantibodies develop when the immune system mistakenly targets components of the thyroid gland or thyroid proteins, leading to chronic inflammation of the thyroid and disruption of thyroid function.

Thyroid stimulating hormone receptor antibodies are autoantibodies that attach to proteins in the thyroid and promote the production of thyroid hormones, leading to hyperthyroidism. Hyperthyroidism, or an overactive thyroid, occurs when the thyroid makes too much of the hormones, thyroxine (T4) and triiodothyronine (T3). An excess of thyroid hormones speeds up metabolism in the body. Hyperthyroidism symptoms include fatigue, unexplained weight loss, heart palpitations, a sensitivity to heat and hair loss.

TSH receptor stimulating antibodies are often associated with Graves' disease and this test helps to investigate symptoms of hyperthyroidism when an autoimmune condition is suspected. It is also used to monitor the progress and effectiveness of anti-thyroid therapy.