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Postal service updates: October - December

TRT (Testosterone Replacement Therapy) Blood Test

TRT (Testosterone Replacement Therapy) Blood Test


A hormone health check for men on testosterone replacement therapy to ensure that hormone levels remain balanced.
Blood sample 24 biomarkers included Results estimated in 2 working days from sample receipt at lab
TRT (Testosterone Replacement Therapy) Blood Test
TRT (Testosterone Replacement Therapy) Blood Test
TRT (Testosterone Replacement Therapy) Blood Test
TRT (Testosterone Replacement Therapy) Blood Test

What's included?

Biomarker profiles

  • Hormones
  • Proteins
  • Clotting Status
  • Red Blood Cells
  • White Blood Cells
  • Prostate

Hormones (4 Biomarkers)

Proteins (4 Biomarkers)

Clotting Status (2 Biomarkers)

Red Blood Cells (7 Biomarkers)

White Blood Cells (6 Biomarkers)

Prostate (1 Biomarker)

Special instructions

Prepare for your TRT (Testosterone Replacement Therapy) Blood Test by following these instructions. Please take your sample before 10am. Avoid heavy exercise for 48 hours beforehand. Please avoid ejaculating for 48 hours prior to this test. Hormonal contraception can affect the results of this test. Taking a break from this and waiting for your periods to restart before your blood test will give more accurate results. Avoid taking your sample from a finger used to apply hormone gels/pessaries/patches in the past 4 weeks. Use gloves to apply these. Do not take biotin supplements for two days before this test, discuss this with your doctor if it is prescribed. If you are a woman take this test two to five days after the start of your period, ideally on day three. It can be taken any time if you do not have periods.

From the expert

Our TRT (Testosterone Replacement Therapy) Blood Test tests for key markers in the blood to help you monitor and manage your testosterone therapy. While testosterone can have a positive impact on strength, libido, sexual performance and mood, there are risks to health, especially if taken to excess. Includes tests for testosterone, free testosterone (calculated), oestrodial, prolactin and SHBG to make sure your hormones remain balanced. We recommend taking this test before starting TRT and 6 months after for monitoring purposes.

You should understand that this test includes a check on your Prostate Specific Antigen (PSA) level. Whilst current research indicates that it is unlikely that testosterone replacement therapy increases the risk of prostate cancer, caution is still advised, particularly for men who already have prostate cancer. 

Whilst the PSA test can help to detect prostate cancer earlier it has several shortcomings when used as a screening test. Besides being increased by prostate cancer PSA can also be increased by innocent conditions such as urinary tract infection, recent ejaculation and even some forms of exercise. This means that there is a risk of PSA being positive when no cancer is present (a false positive). If we take 100 men with a high PSA result then approximately 75 of them will have a false positive result, and 25 will have a true positive (i.e. they will have prostate cancer). Currently the most reliable way of working out whether someone has a true positive or a false positive is by performing a prostate biopsy. Because the PSA test has a high false positive rate many of these prostate biopsies will have been unnecessary.  

You should also be aware that PSA tests can cause false negative results. This means that the PSA is in the normal range but the person has underlying prostate cancer. PSA levels can remain normal in the early stages of prostate cancer, providing false reassurance. If we test 100 men with prostate cancer then approximately 15 of them would have a normal PSA result (a false negative). In some cases prostate cancer grows very slowly and may never cause symptoms or shorten lifespan, so a significant proportion of the men who receive a true positive result may undergo surgery that they did not need.

Dr Sam Rodgers MBBS, MRCGP
Chief Medical Officer

Why take this test?

  • You are are male and have been taking testosterone replacement therapy and wish to monitor your hormones
  • You recognise there can-be side effects with TRT and you want to minimise your risks

Laboratories you can trust

Trusted by the NHS and private clinics alike, you can be sure of the highest testing standards from our UKAS accredited partner laboratories.

Dr Sam Rodgers - Chief Medical Officer

Expert advice with your results

Get trusted advice and comments from one of our doctors based on your results.

Your personal health centre

Your personal health centre

Discover the easy way to track your health through our online portal, View your results with doctor's advice, monitor any changes over time and see the improvements you can make to your health with simple lifestyle changes.

Questions? Let us help
Questions? Let us help

Questions? Let us help

Our customer care team is on-hand to help you find the test that's right for you. Get in touch via phone, live chat or email.


Our tests are not a substitute for seeing your doctor, especially if you are suffering symptoms. Our doctors will interpret your results based on the information you have provided, but will not diagnose, consult or provide any treatment. You will be advised to see your doctor for any necessary follow-up action.