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Advanced Tiredness and Fatigue Blood Test

Advanced Tiredness and Fatigue Blood Test


An advanced blood test to investigate why you might be feeling tired all the time. With tests for anaemia, vitamin D, thyroid health, iron status, B vitamins and diabetes.
Blood sample 26 biomarkers included Results estimated in 3 working days from sample receipt at lab
Advanced Tiredness and Fatigue Blood Test
Advanced Tiredness and Fatigue Blood Test
Advanced Tiredness and Fatigue Blood Test
Advanced Tiredness and Fatigue Blood Test

Is it for you?

Is fatigue becoming a normal part of your everyday? Do you want a comprehensive check of the main causes of fatigue so that you can seek treatment and get your energy back? If you are looking for a medical reason for why you feel tired all the time, this profile is right for you. It covers many of the main causes of fatigue including diabetes, anaemia, an underactive thyroid and vitamin deficiencies.

What's included?

Biomarker profiles

  • Diabetes
  • Iron Status
  • Thyroid Hormones
  • Clotting Status
  • Red Blood Cells
  • White Blood Cells
  • Vitamins
  • Inflammation

Diabetes (1 Biomarker)

Iron Status (4 Biomarkers)

Thyroid Hormones (2 Biomarkers)

Clotting Status (2 Biomarkers)

Red Blood Cells (7 Biomarkers)

White Blood Cells (6 Biomarkers)

Vitamins (3 Biomarkers)

Inflammation (1 Biomarker)

Special instructions

Please take your sample in the morning. CRP levels can be affected by infection, inflammation, and illness. If you are taking this test because you have recently developed symptoms or they are worsening you should discuss these with your doctor. We suggest taking your test when any short-term change in your symptoms have settled. Do not take vitamin B12 for two weeks prior to this test. If your B12 is prescribed ask your doctor whether you should stop before testing. Do not take biotin supplements for 2 days prior to this test. If you are taking prescribed biotin you should discuss this with your doctor. You should take this test before you take any vitamin or mineral supplements.

From the expert

This blood test is an advanced version of our Tiredness and Fatigue Blood Test and includes tests which must be done with a venous sample (blood taken from a vein in your arm) as opposed to a finger-prick sample. This means that we can test more markers, and can include a full blood count where we look at the number, size and shape of your red blood cells. If your red blood cells are abnormal it affects their ability to transport oxygen around your body, a common cause of fatigue.

Feeling tired all the time is one of the most common reasons why people visit their doctor, but sometimes finding out the reasons for your symptoms can be a journey of trial and error. This advanced fatigue profile aims to get to the cause of low energy levels by looking at many of the common causes of fatigue. 

Often fatigue is caused by anaemia, either from iron deficiency or because of low levels of B vitamins which are essential for the creation of normal red blood cells. This profile checks your iron status and active vitamin B12 levels, but also takes a detailed look at your red blood cells to make sure that they show no signs of anaemia. We also look at your white blood cells to check that infection or inflammation is not contributing to your symptoms, as well as vitamin D deficiency, a very common cause of low energy and aches and pains. 

Other causes of fatigue include diabetes and an underactive thyroid and this profile includes tests for both conditions.

Dr Sam Rodgers MBBS, MRCGP
Chief Medical Officer

Why take this test?

  • You are abnormally tired and want to know why
  • You want to get your energy back so that you can live your life normally
  • You have more aches and pains than usual
  • You want a comprehensive check for the main causes of low energy

Laboratories you can trust

Trusted by the NHS and private clinics alike, you can be sure of the highest testing standards from our UKAS accredited partner laboratories.

Dr Sam Rodgers - Chief Medical Officer

Expert advice with your results

Get trusted advice and comments from one of our doctors based on your results.

Your personal health centre

Your personal health centre

Discover the easy way to track your health through our online portal, View your results with doctor's advice, monitor any changes over time and see the improvements you can make to your health with simple lifestyle changes.

Questions? Let us help
Questions? Let us help

Questions? Let us help

Our customer care team is on-hand to help you find the test that's right for you. Get in touch via phone, live chat or email.


Our tests are not a substitute for seeing your doctor, especially if you are suffering symptoms. Our doctors will interpret your results based on the information you have provided, but will not diagnose, consult or provide any treatment. You will be advised to see your doctor for any necessary follow-up action.