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We recommend that you do not collect or post samples between Tuesday 31st and Sunday 5th June.

Methylmalonic Acid (MMA) Blood Test

Methylmalonic Acid (MMA) Blood Test


This blood test measures methylmalonic acid levels to help diagnose vitamin B12 deficiency after a B12 test is low or at the lower end of normal.
Blood sample 1 biomarker included Results estimated in 10 working days from sample receipt at lab
Methylmalonic Acid (MMA) Blood Test
Methylmalonic Acid (MMA) Blood Test
Methylmalonic Acid (MMA) Blood Test
Methylmalonic Acid (MMA) Blood Test

What's included?

Biomarker profile

  • Vitamins

Vitamins (1 Biomarker)

Special instructions

Do not take vitamin B12 for two weeks prior to this test. If your B12 is prescribed ask your doctor whether you should stop before testing.

From the expert

Methylmalonic acid is produced in small amounts in the body, necessary for metabolism and energy production. Vitamin B12 promotes the conversion of methylmalonyl CoA to succinyl Coenzyme A. If there is not enough vitamin B12 available in the body, then the concentration of methylmalonic acid begins to rise, resulting in an increase in the blood and urine.

The measurement of raised methylmalonic acid levels in the blood or urine is a useful and sensitive early indicator of a vitamin B12 deficiency. Vitamin B12 deficiency symptoms usually develop gradually but can worsen if the condition goes untreated, they include feeling faint, pale skin and palpitations.

This test measures the level of methylmalonic acid in the blood.

Dr Sam Rodgers MBBS, MRCGP
Chief Medical Officer

Why take this test?

  • You want an early indicator of a vitamin B12 deficiency

Laboratories you can trust

Trusted by the NHS and private clinics alike, you can be sure of the highest testing standards from our UKAS accredited partner laboratories.

Dr Sam Rodgers - Chief Medical Officer

Expert advice with your results

Get trusted advice and comments from one of our doctors based on your results.

Your personal health centre

Your personal health centre

Discover the easy way to track your health through our online portal, View your results with doctor's advice, monitor any changes over time and see the improvements you can make to your health with simple lifestyle changes.

Questions? Let us help
Questions? Let us help

Questions? Let us help

Our customer care team is on-hand to help you find the test that's right for you. Get in touch via phone, live chat or email.


Our tests are not a substitute for seeing your doctor, especially if you are suffering symptoms. Our doctors will interpret your results based on the information you have provided, but will not diagnose, consult or provide any treatment. You will be advised to see your doctor for any necessary follow-up action.