Intrinsic Factor Antibodies Blood Test

Intrinsic factor is a glycoprotein produced by the parietal cells in the stomach and is necessary for the absorption of vitamin B12 from the food we eat. Interference in the production or activity of intrinsic factor can reduce the absorption of vitamin B12 in the small bowel resulting in anaemia.
This blood test identifies whether antibodies to intrinsic factor are present which would indicate pernicious anaemia, an autoimmune condition.

Pernicious anaemia causes a deficiency in vitamin B12, an essential water-soluble vitamin found in virtually all meat products and certain algae such as seaweed. It helps maintain healthy nerve cells and red blood cells and is also required to make DNA, the genetic material in all cells. Symptoms of pernicious anaemia include, fatigue, shortness of breath, brittle nails, pins and needles and cognitive difficulties (brain fog). Symptoms of pernicious anaemia can become debilitating and can cause lasting damage if not caught early enough. Pernicious anaemia can be treated by regular vitamin B12 injections.