Skip to content

Covid-19 Antibody Test with clinic visit available for £99. Shop now

Stress Cortisol Saliva Tests (6)
Stress Cortisol Saliva Tests (6)
Stress Cortisol Saliva Tests (6)
Stress Cortisol Saliva Tests (6)

Stress Cortisol Saliva Tests (6)

A simple saliva test which measures your cortisol levels 6 times throughout the day to assess stress levels and how well your adrenal glands are functioning.
Saliva sample 6 biomarkers included 2 working days turnaround

What's included?

Biomarker profile

  • Adrenal Hormones

Adrenal Hormones (6 Biomarkers)

Special instructions

Samples are taken after waking, 12 noon, 2pm, 4pm, 6pm and before going to sleep. If you are tracking your results over time then it is vital that you always take your samples at the same time. High dose biotin supplements can affect this test. If you are taking more than the recommended daily amount then you should not take your supplements for 2 days prior to this test. If you are taking high dose biotin for medical reasons (e.g. multiple sclerosis) then you should discuss this with your doctor. Use of the oestrogen containing medications such as hormone replacement therapy or the combined oral contraceptive pill can cause elevated cortisol readings. This test can be affected by corticosteroid medications such as prednisolone. If you are taking a corticosteroid medication then we recommend that you discuss with your doctor whether this test is needed, and if so whether you should continue taking your corticosteroid medication. Do not consume food or drink for thirty minutes before your test. Do not brush your teeth for thirty minutes before your test. If your saliva sample gets contaminated by food, drink or even small amounts of blood (e.g. from your gums after brushing your teeth) then your result may be affected.
Chronic stress can be very bad for our health and can lead to an impaired immune system as well as problems with energy levels, fat retention and sleep. Cortisol is a steroid hormone which is produced in the adrenal glands and is your body's main stress hormone. It is vital for survival given its role in various functions such as immunity, regulating blood pressure and releasing insulin for blood sugar maintenance. Cortisol has been termed 'the stress hormone' because it is secreted in higher quantities during the body's 'fight or flight' response to stress, and is responsible for several stress-related changes in the body.

This test measures the levels of cortisol in your saliva at 6 different points in the day. Samples are taken after waking, 12 noon, 2pm, 4pm, 6pm and before going to sleep. Cortisol levels should be highest just after waking in the morning and lowest at bedtime; this is called diurnal rhythm. This test will tell you whether your cortisol levels are normal for the time of day, or whether you need to be taking action to reduce the amount of stress in your day-to-day life. 

As well as helping you to see if you are experiencing too much stress, this test can also help identify medical conditions such as Cushing's syndrome, which is caused by too much cortisol, or Addison's disease, which is caused by damage to the adrenal glands and is associated with too little cortisol. 

Please note that the lower detection limit for this test is 1.5 nmol/L.

Dr Sam Rodgers MBBS, MRCGP

Why take this test?

  • You want to manage your stress levels by understanding your cortisol rhythm
  • You crave sugar and carbohydrates late in the day
  • You find it difficult to wake in the morning and to get to sleep at night
  • You are often under the weather and want to see if this might be stress related

3 simple steps

  • Take the test

    Take the test - either using your kit or visit a clinic.
  • Post your sample

    Send your sample in the freepost pack to our fully accredited lab.
  • Get your results

    Get your doctor reviewed results on
Expert interpretation<br>
of your results

Expert interpretation
of your results

One of our team of doctors will review your results and give you personalised advice based on your medical history, lifestyle and health and fitness goals.

Your personal<br>
health centre

Your personal
health centre

Discover the easy way to track your health through our online portal, View your results with doctor's advice, monitor any changes over time and see the improvements you can make to your health with simple lifestyle changes.

Questions? Let us help

Questions? Let us help

Our customer care team are on-hand to help you find the test that's right for you. Get in touch via phone, live chat or email.

Laboratories you can trust

Trusted by the NHS and private clinics alike, you can be sure of the highest testing standards from our partner laboratories

What our customers say

We ask every Medichecks customer about their experience - read what they have to say


Our tests are not a substitute for seeing your doctor, especially if you are suffering symptoms. Our doctors will interpret your results based on the information you have provided, but will not diagnose, consult or provide any treatment. You will be advised to see your doctor for any necessary follow-up action.