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Porphyrins Stool Test
Porphyrins Stool Test

Porphyrins Stool Test

A test for porphyria, an inherited condition which affects the body's ability to produce heme, a component of red blood cells.

Is it for you?

Are you experiencing symptoms such as severe stomach pain and nausea, mental confusion, muscle pain, tingling and numbness? Do you have a family member who has been diagnosed with porphyria? If you have current symptoms and want to confirm or rule out porphyria, this is the test for you.
Stool sample 1 biomarker included 14 working days turnaround
from sample receipt at lab

What's included?

Biomarker profile

  • Metabolic Disorders

Metabolic Disorders (1 Biomarker)

Special instructions

Wrap your sample in foil immediately after it is taken.

Porphyrins are a group of chemicals that help form many important substances in the body, including haemoglobin. A porphyrins test is used to diagnose porphyrias, which are a group of rare disorders often passed down through family members.


Porphyria is an inherited disorder in which the body produces too much of the chemical porphyrin. Any circulating porphyrin the body doesn't use is excreted in urine and stool. Porphyria is a term that refers to a group of disorders that affect the nervous system or skin, or both.

Each type of porphyria is due to the deficiency of one of the enzymes needed to make a substance in the body called haeme. Making haeme involves a series of eight different enzymes, each acting in turn.


Haeme is a red pigment composed of iron linked to a chemical called protoporphyrin. Haeme has important functions in the body. The largest amounts of haeme are in the blood and bone marrow in the form of haemoglobin within red blood cells. Haemoglobin gives blood its red color and carries oxygen from the lungs to all parts of the body.


In the liver, haeme is a component of proteins that have many functions, including breaking down hormones, drugs, and other chemicals and generating high-energy compounds that keep liver cells alive and functioning normally.


The body makes haeme mostly in the bone marrow and the liver. Each step of the process is controlled by one of eight enzymes. If any one of the enzymes is deficient, the process is disrupted. As a result, porphyrin or its precursors—chemicals formed at earlier steps of the process—may build up in body tissues and cause illness.

Dr Sam Rodgers MBBS, MRCGP

How it works

  • Take the test

    Collect your sample at home, visit a partner clinic, or we can even send a nurse to you.
  • Post your sample

    Send your sample back on the same day you take it in the freepost pack to our laboratory.
  • Get your results

    View your results with doctor's advice on your personal dashboard.
Laboratories you can trust

Laboratories you can trust

Trusted by the NHS and private clinics alike, you can be sure of the highest testing standards from our fully accredited partner laboratories.

Expert interpretation <br>
of your results

Expert interpretation
of your results

One of our team of doctors will review your results and give you personalised advice based on your medical history, lifestyle and health and fitness goals.

Your personal<br>
health centre

Your personal
health centre

Discover the easy way to track your health through our online portal, my.medichecks.com. View your results with doctor's advice, monitor any changes over time and see the improvements you can make to your health with simple lifestyle changes.

Questions? Let us help

Questions? Let us help

Our customer care team is on-hand to help you find the test that's right for you. Get in touch via phone, live chat or email.

What our customers say

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Important

Our tests are not a substitute for seeing your doctor, especially if you are suffering symptoms. Our doctors will interpret your results based on the information you have provided, but will not diagnose, consult or provide any treatment. You will be advised to see your doctor for any necessary follow-up action.