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Methylmalonic Acid (MMA) Urine Test
Methylmalonic Acid (MMA) Urine Test

Methylmalonic Acid (MMA) Urine Test

This urine test measures methylmalonic acid levels to help diagnose vitamin B12 deficiency after a B12 test is low or at the lower end of normal.
Urine sample 3 biomarkers included 16 working days turnaround
from sample receipt at lab

What's included?

Biomarker profiles

  • Vitamins
  • Kidney Health

Vitamins (2 Biomarkers)

Kidney Health (1 Biomarker)

Special instructions

Do not take vitamin B12 for two weeks prior to this test. If your B12 is prescribed ask your doctor whether you should stop before testing.
Methylmalonic acid is produced in small amounts in the body, necessary for metabolism and energy production. Vitamin B12 promotes the conversion of methylmalonyl CoA to succinyl Coenzyme A. If there is not enough vitamin B12 available in the body, then the concentration of methylmalonic acid begins to rise, resulting in an increase in the blood and urine.

The measurement of raised methylmalonic acid levels in the blood or urine is a useful and sensitive early indicator of a vitamin B12 deficiency. Vitamin B12 deficiency symptoms usually develop gradually but can worsen if the condition goes untreated. Symptoms include fatigue, feeling faint, pale skin and heart palpitations.

This test measures the level of methylmalonic acid in the urine.

Dr Sam Rodgers MBBS, MRCGP

Why take this test?

  • You want an early indicator of a vitamin B12 deficiency
Laboratories you can trust

Laboratories you can trust

Trusted by the NHS and private clinics alike, you can be sure of the highest testing standards from our fully accredited partner laboratories.

Expert interpretation <br>
of your results

Expert interpretation
of your results

One of our team of doctors will review your results and give you personalised advice based on your medical history, lifestyle and health and fitness goals.

Your personal<br>
health centre

Your personal
health centre

Discover the easy way to track your health through our online portal, View your results with doctor's advice, monitor any changes over time and see the improvements you can make to your health with simple lifestyle changes.

Questions? Let us help

Questions? Let us help

Our customer care team is on-hand to help you find the test that's right for you. Get in touch via phone, live chat or email.

What our customers say

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Our tests are not a substitute for seeing your doctor, especially if you are suffering symptoms. Our doctors will interpret your results based on the information you have provided, but will not diagnose, consult or provide any treatment. You will be advised to see your doctor for any necessary follow-up action.