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TSH Receptor Antibodies


TSH receptor antibodies cause Graves' disease hyperthyroidism. Graves’ disease is caused by the direct stimulation of the thyroid cells by TSH receptor stimulating antibodies. All forms of autoimmune thyrotoxicosis (Graves’ disease, Hashitoxicosis, neonatal thyrotoxicosis) are caused by the production of TSH receptor antibodies. These antibodies stimulate the thyroid gland independent of the normal regulated TSH stimulation.