Total Protein represents the sum of the proteins albumin and globulin in your blood. Albumin and globulin have a range of functions including keeping blood within vessels, transporting nutrients and fighting infection. Abnormal levels can indicate malnutrition as well as a liver or kidney disorder.
What might a low result mean?
Low levels can be found in individuals with liver diseases, when the liver is not producing sufficient protein, and in kidney diseases, where the kidneys allow too much protein to be passed out of the body in the urine.
Low levels can also indicate gastrointestinal disorders such as coeliac disease and Crohn's disease, in which insufficient amounts of proteins are absorbed.
What might a high result mean?
Elevated levels of total protein are usually mild and transient and may indicate infections. This is due to an influx of proteins such as antibodies into the blood to help fight the infection.
Raised levels of total protein can also occasionally be found in medical conditions including certain bone marrow diseases such as Waldenstrom's disease and multiple myeloma, where the bone marrow produces excessive amounts of protein.