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Pregnenolone is a chemical that is a precursor to all steroid hormones in the body. For normal steroid hormone production, cholesterol is converted into pregnenolone in the adrenal glands and then several enzymes complete the production of multiple hormones. A Pregnenolone test helps to monitor and/or rule out two of the more rare forms of congenital adrenal hyperplasia (CAH).

What might a high result mean?

If there is an enzyme deficiency in the steroid hormone production process, there is likely to be a mild to significant increase in pregnenolone.