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MPV, or Mean Platelet Volume, is a measurement of the average size of your platelets. Platelets are fragmented cells within the blood that aid the process of clot formation. MPV provides an indication of platelet production in your bone marrow.

What might a low result mean?

Low levels of MPV indicate that your platelets are small, or that a reduced number of platelets are being produced. This may indicate a bone marrow disorder, including the effects of chemotherapy on the bone marrow.

Low levels of MPV may also be found in people with inflammatory bowel disease and aplastic anaemia, however other blood biomarkers would need to be assessed in order to arrive at these diagnoses.

What might a high result mean?

Raised levels of MPV can be found when increased numbers of platelets are being produced. This is because newer platelets are larger than older ones, and so the presence of recently produced platelets increases the MPV value. Elevated levels for MPV can also be found in people with a range of conditions including hyperthyroidism, hypertension, and diabetes.