Insulin-Like Growth Factor 1 (Somatomedin C) is a hormone which helps to control how rapidly the body's cells grow and reproduce. Although a high level of IGF-1 is necessary for growth in children, there are negative implications in adulthood.
What might a low result mean?
A decrease in IGF-1 may be due to a decrease in pituitary function (hypopituitarism), nutritional deficiencies and chronic kidney or liver disease.
What might a high result mean?
Increased IGF-1 levels are are normal during puberty and pregnancy but are otherwise most frequently seen in those who have pituitary tumours (usually benign). Having a high IGF-1 has also been associated with the reproduction of cancer cells, and also the ageing process.