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Globulin is an umbrella term for a set of different proteins that the immune system and the liver produce. Certain globulins bind with haemoglobin while others transport metals, such as iron, in the blood. Additionally, there is a certain type of globulin known as an immunoglobulin, (another name for an antibody) which helps to fight infection in the body.

What might a low result mean?

Low levels of globulin may be found in individuals with nephrosis (a condition in which the kidneys do not filter the protein from the blood and it leaks into the urine), acute haemolytic anaemia and liver disease.

What might a high result mean?

Elevated levels of globulin may be found in individuals suffering from chronic infections (parasites, viral and bacterial), liver disease, rheumatoid arthritis and certain autoimmune diseases including systemic lupus and collagen diseases.