Anticardiolipin antibodies are the most common form of antiphospholipid antibodies. These are molecules produced by the body which target mitochondria in cells for destruction. There are two types of antibodies attacking mitochondria in this way; IgM and IgG. IgG is the autoantibody most commonly associated with clinical symptoms, however IgM is also detected in some cases.
What might a low result mean?
It is common to have no anticardiolipin antibodies in your blood. However, low levels may be detected in people as they age, or in individuals who have recently had an infection.
What might a high result mean?
Raised levels of anticardiolipin antibodies can be found in people with an autoimmune condition called antiphospholipid syndrome. Affected individuals are more likely to develop dangerous blood clots and to experience pregnancy complications.
Elevated levels are also found in individuals with lupus and syphilis.